![]() “During the week after each experimental session, the most commonly reported reactions at any severity were anxiety, fatigue, insomnia, depressed mood, hypersomnia, difficulty concentrating, decreased appetite, and dizziness in the active dose MDMA groups across studies, with PTSD studies overrepresented. Immune functioning: “MDMA may also produce modest changes in immune functioning, lasting up to 48 hours.” 3.Once the drug leaves the body, 3 to 4 days post-treatment, most reactions diminish.” 1 “Common reactions reported in clinical trials are transient and diminish as drug effects wane during the MDMA session and over the next 24 hours. Possible side effects during the next few days Overcompensating by drinking too much water can be fatal. 12 Dancing aerobically in hot environments causes dehydration. Generally caused by drinking too much water. Like all serotonergic drugs, MDMA increases heat stroke risk due to its effects on the hypothalamus, the part of our brain that helps us regulate body temperature. Many tablets and powders are fake and/or adulterated with other drugs. For comparison, there’s a “0.0007% chance of dying from a skydive, compared to a 0.0167% chance of dying in a car accident” based on driving 10,000 miles. 4 5 Harm reduction expert Emanuel Sferios estimated that there are around 20 ecstasy related deaths per year in the US. In the absence of any symptoms of coronary insufficiency, the investigator judged the only medical measure necessary to be withholding the supplemental dose of MDMA.” “Full recovery occurred 1 day after MDMA administration.” 1 Side effect during useĪverage proportion of MDMA clinical trial participants who experienced this side effect, increase over placebo group 1Ībout 2.66 million people used ecstasy in the US in 2015. ![]() ![]() ![]() The subject had no other signs and no symptoms of cardiac distress. Subject 0811 experienced an increase in frequency of ventricular extrasystoles (PVC’s), a form of arrhythmia, on the day of his third and final experimental session with open-label 125 mg MDMA. “MDMA has been administered to more than 750 human subjects in clinical studies with only one single serious adverse event occurring as a result of the drug.” 3ĭetails of the single serious adverse effect: “One related serious adverse reaction has occurred within all sponsor-supported studies to date. That’s the worst case we’ve seen in all of the trials.” 2 The physician on-site decided, “Oh, we’re not so sure about this,” so the patient went to the emergency room and was released later that day with no treatment. Out of the 136 subjects who were treated in the Phase 2 studies, only one 50-year-old male had an elevated heart rate. But in all our studies so far, we’ve kept the blood pressure constant to that of the room. There’s also heightened cardiovascular activity - you might get a slightly higher heart rate or a slightly higher blood pressure level. You want to bring up anxiety, but it’s reported as a side effect. “There can be acute nervousness or anxiety during the psychotherapy session, but that’s to be expected, because again, that’s the drug bringing out the effects of PTSD. “Overall, adverse effects of MDMA are modest and generally have not been associated with serious discomfort in healthy volunteers or in people with PTSD.” “Common reactions reported in clinical trials are transient and diminish as drug effects wane during the MDMA session and over the next 24 hours. Side effects of pure MDMA Possible side effects during use To learn how pure Molly (MDMA) makes you feel, visit this page.
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